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A rare genetic disorder causes the hard matrix of a certain connective tissue to become less rigid, leading to frequent bone fractures. What is the most likely explanation for this observation?
Decrease in plasma proteins in blood matrix
Loss of proteins and sugars in cartilage matrix
A defect in type I collagen due to Mutation in COL1A1 or COL1A2 genes
Reduction in calcium and phosphorus compounds in bone matrix
A defect in type I collagen due to Mutation in COL1A1 or COL1A2 genes
Practice and solve "A rare genetic disorder causes the hard matrix of a certain connective tissue to become less rigid, ..." for General Science - Previous Year Paper 2026. The correct answer is Option C: A defect in type I collagen due to Mutation in COL1A1 or COL1A2 genes. Detailed step-by-step solution, conceptual clarity, and formulas on Examoogle.
Practice and solve "A rare genetic disorder causes the hard matrix of a certain connective tissue to become less rigid, ..." for General Science - Previous Year Paper 2026. The correct answer is Option C: A defect in type I collagen due to Mutation in COL1A1 or COL1A2 genes. Detailed step-by-step solution, conceptual clarity, and formulas on Examoogle.