African Swine Fever is a highly contagious viral disease that poses a significant threat to the domestic and wild pig population, causing severe economic losses in the livestock sector. Since the disease was first detected in India in 2020, there has been no effective treatment or cure, making the development of a vaccine crucial. The new indigenous vaccine, developed by ICAR-NIHSAD, utilizes the MA-104 cell line technology to provide a preventive solution. This achievement aligns with the broader national goal of promoting veterinary research and safeguarding animal health security.