Join 60,000+ competitive exam aspirants
What is required for the synthesis of thyroxin hormones?
Nickel
Bromine
Iodine
Chlorine
Iodine
Iodine is an essential mineral required by the thyroid gland for the synthesis of thyroxine hormone (T4тАЛ). A deficiency of iodine leads to inadequate hormone production, resulting in enlargement of the thyroid gland, a condition known as goitre.
Iodine is an essential mineral required by the thyroid gland for the synthesis of thyroxine hormone (T4тАЛ). A deficiency of iodine leads to inadequate hormone production, resulting in enlargement of the thyroid gland, a condition known as goitre.
Think of iodine as the key ingredient in a bakery recipe; without this specific ingredient (iodine), the baker (thyroid gland) cannot bake the final product (thyroxine hormone), no matter how much flour or sugar is present.
I-O-D-I-N-E makes T-H-Y-R-O-X-I-N-E (Thyroid needs Iodine).
T4тАЛ тАФ Tetraiodothyronine (Thyroxine)
T3тАЛ тАФ Triiodothyronine
The thyroid gland takes up inorganic iodide from the bloodstream and transports it into follicular cells where it is oxidized to iodine. This iodine is then incorporated into the amino acid tyrosine residues on thyroglobulin molecules to form monoiodotyrosine (MIT) and diiodotyrosine (DIT), which subsequently couple to form thyroxine (T4тАЛ) and triiodothyronine (T3тАЛ).
Thyroxine regulates the basal metabolic rate (BMR) of the body.
It controls carbohydrate, fat, and protein metabolism.
Iodine deficiency causes endemic goitre, characterized by swelling in the neck.
During pregnancy, iodine deficiency leads to cretinism in children (stunted growth and mental retardation).
Maintains normal metabolic rate and energy balance.
Supports proper physical and mental development in children.
Diagnosis of thyroid disorders using radioactive iodine (131I).
Iodized salt programs implemented globally to prevent iodine deficiency disorders (IDD).
Option C (Iodine) is correct as it is the central halogen atom in the molecular structure of thyroid hormones (T3тАЛ and T4тАЛ).
Nickel, Bromine, and Chlorine are not utilized in human thyroid hormone synthesis.
C is correct тАФ Iodine is an essential trace element required by the thyroid gland to synthesize thyroxine hormone.
Questions on endocrine glands and their hormone deficiencies frequently appear in RRB and SSC exams. Remember: Iodine тЖТ Thyroid тЖТ Thyroxine тЖТ Goitre.